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1987-10-07
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581b
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16 lines
IN PATIENTS WITH RENAL IMPAIRMENT, CLOFIBRATE DOSAGE SHOULD
BE CAREFULLY ADJUSTED TO AVOID TOXICITY (MYOSITIS,
ARTHRALGIA).
SOME CLINICIANS RECOMMEND THAT THE DOSAGE REGIMEN BE
ADJUSTED BASED ON THE PATIENT'S CREATININE CLEARANCE:
CREATININE DOSAGE INTERVAL
CLEARANCE METHOD
(ML/MINUTE)
10-50 12 to 18 hours
<10 24 to 48 hours